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The First 2,000 Rescues: Cyanokit Use and Victim Burns with Survival Rate

5/15/2021

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Data Drop...Cyanokit Use and Victim Burns v Survival Rate.

While the sample size of victims given hydroxocobalamin (Cyanokit) is relatively small (n = 204 total), the numbers are definitely intriguing (this is obviously not a double-blind, peer reviewed, empirical study that meets the standard of the medical community). As you can see in the raw data and graph below, the survival rate for all three burn categories is higher when hydroxocobalamin is given to the vicitm. As always there are multiple variables at play, but we'll be keeping an eye on these numbers in future iterations for sure. As always, the more we learn, the more questions that arise:

Does your department/local transporting agency carry hydroxocobalamin?

If not, why (price, shelf-life, etc.)? Could you/they work with a local hospital/burn center to stock the medication?

What are your/their indications for giving hydroxocobalamin?

Victim Burns v Cyanokit v Survival Rate:
None – (no Cyanokit) 72% (654/910) ; (Cyanokit) 77% (82/106)
Mild - (no Cyanokit) 57% (230/407) ; (Cyanokit) 64% (42/66)
Severe - (no Cyanokit) 37% (151/409) ; (Cyanokit) 53% (17/32)

A big thanks to Robert McClelland for all his work on this topic.
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